About Justin

Justin Klesmith is a PostDoc in the department of Chemical Engineering and Materials Science at the University of Minnesota. Graduate work was performed at the Whitehead Lab focused on protein design and metabolic pathway development.

Publications

The interrelationship between promoter strength, gene expression, and growth rate

Matthew S Bienick, Katherine W Young, Justin R Klesmith, Emily E Detwiler, Kyle J Tomek, Timothy A Whitehead
Published: October 6, 2014 DOI: 10.1371/journal.pone.0109105
Related Content: AddGene

High-Resolution Sequence-Function Mapping of Full-Length Proteins

Caitlin A. Kowalsky, Justin R. Klesmith, James A. Stapleton, Vince Kelly, Nolan Reichkitzer, Timothy A. Whitehead
Published: March 19, 2015 DOI: 10.1371/journal.pone.0118193

Producing glucose-6-phosphate from cellulosic biomass: structural insights into levoglucosan bioconversion

John-Paul Bacik, Justin R. Klesmith, Timothy A. Whitehead, Laura R. Jarboe, Clifford Unkefer, Brian L. Mark, Ryszard Michalczyk
Published: September 9, 2015 DOI: 10.1074/jbc.M115.674614

Comprehensive sequence-flux mapping of a levoglucosan utilization pathway in E. coli

Justin R. Klesmith, John-Paul Bacik, Ryszard Michalczyk, Timothy A. Whitehead
Publication Date (Web): September 14, 2015 DOI: 10.1021/acssynbio.5b00131
Related Content: GitHub FigShare AddGene PDB: 4ZXZ

High-throughput evaluation of synthetic metabolic pathways

Justin R. Klesmith, Timothy A. Whitehead
Published: December 16, 2015 DOI: 10.1142/S233954781640001X
PDF: High-throughput evaluation of synthetic metabolic pathways

Plasmid-based one-pot saturation mutagenesis

Emily E. Wrenbeck, Justin R. Klesmith, James A. Stapleton, Adebola Adeniran, Keith E. J. Tyo, Timothy A. Whitehead
Published: September, 9 2016 DOI: 10.1038/nmeth.4029

Fine Epitope Mapping of Two Antibodies Neutralizing the Bordetella Adenylate Cyclase Toxin

Xianzhe Wang, James A. Stapleton, Justin R. Klesmith, Erik L. Hewlett, Timothy A. Whitehead, and Jennifer A. Maynard
Published: February 8, 2017 DOI: 10.1021/acs.biochem.6b01163

Trade-offs between enzyme fitness and solubility illuminated by deep mutational scanning

Justin R. Klesmith, John-Paul Bacik, Emily E. Wrenbeck, Ryszard Michalczyk, and Timothy A. Whitehead
Published: February 14, 2017 doi: 10.1073/pnas.1614437114

Education

Michigan State University

East Lansing, MI
PhD - Biochemistry and Molecular Biology
Advisor: Timothy A. Whitehead, PhD

University of Wisconsin - Stevens Point

Stevens Point, WI
BS - Biochemistry
Advisor: Thomas Zamis, PhD
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